The Huntress is extremely proficient at "kiting" (running and firing while remaining unhurt). Remember that Laser Glaive does the highest damage on the last bounce! Blink can be used to reposition or re-aim abilities, and Cluster Bomb can take out grouped enemies at range.
The Huntress benefits from both on hit and on kill items. Laser Glaive will proc on-hit items on each bounce. (Compared to most skills, which normally count as one hit, such as the Mercenary's Whirlwind.)
The Huntress can run backwards if you remain firing, allowing you to be on the move while dealing damage
Combining the Wicked Ring with a decent critical chance (be it from Lens-Maker's Glasses or other crit-based items) allows the huntress to use her Laser Glaive almost as a primary attack, especially in later levels. Since it bounces to a maximum of four enemies, with a 100% critical chance, each arrow will reset the timer, as well as one second's worth of the timer after it, allowing for extremely rapid firing of the Laser Glaive.